Name Steward Organization Suggested Domain Suggested Domain Description Cde Group Classification
Antithrombotic Therapy Change Reason NHLBI Treatment
Treatment for all conditions
NIH CDEs
  • NHLBI
    • Venous Thromboembolism (VTE)
      • Pharmacotherapy
        • Antithrombotics
          • Characteristics

# Datatype
Value List

# Permissible value Value meaning name
Change in creatinine clearance Change in creatinine clearance
Change in goals of care Change in goals of care
Change in liver function Change in liver function
Change in weight Change in weight
Completion of Therapy Completion of Therapy
Cost Cost
Death Death
Dose adjustment based on laboratory monitoring Dose adjustment based on laboratory monitoring
Drug-drug interaction caused by change in concomitant medication(s) Drug-drug interaction caused by change in concomitant medication(s)
Failure of therapy due to new or progressive VTE Failure of therapy due to new or progressive VTE
Intolerance of therapy due to bleeding Intolerance of therapy due to bleeding
Intolerance of therapy due to non-bleeding adverse event Intolerance of therapy due to non-bleeding adverse event
Lack of availability Lack of availability
Other reason Other reason

# Definition
The reason(s) for a change in active antithrombotic pharmacotherapy. Changes can include discontinuation of therapy, change in dose, change in frequency, change in product, or change in route of administration.

# Designation Tags
Antithrombotic Therapy Change Reason
Reason for Changing Pharmacotherapy Suggested Question Text

# Identifier Origin Version
gGur_P2NLK NLM CDEs 12-02-2025-download
17:6:6:3 ISTH N/A