|
|
Acute renal failure
|
Sudden and sustained deterioration of the kidney function characterized by decreased glomerular filtration rate, increased serum creatinine or oliguria. C26808
|
C26808
|
NCI Thesaurus
|
|
|
Acute respiratory distress syndrome (ARDS)
|
Progressive and life-threatening pulmonary distress in the absence of an underlying pulmonary condition, usually following major trauma or surgery. Cases of neonatal respiratory distress syndrome are not included in this definition. C3353
|
C3353
|
NCI Thesaurus
|
|
|
Anemia
|
A reduction in the number of red blood cells, the amount of hemoglobin, and/or the volume of packed red blood cells. Clinically, anemia represents a reduction in the oxygen-transporting capacity of a designated volume of blood, resulting from an imbalance between blood loss (through hemorrhage or hemolysis) and blood production. Signs and symptoms of anemia may include pallor of the skin and mucous membranes, shortness of breath, palpitations of the heart, soft systolic murmurs, lethargy, and fatigability. C2869
|
C2869
|
NCI Thesaurus
|
|
|
Appendicitis
|
Acute inflammation of the vermiform appendix. C35145
|
C35145
|
NCI Thesaurus
|
|
|
Arterial Thrombosis
|
Formation of a blood clot in the lumen of an artery. C98826
|
C98826
|
NCI Thesaurus
|
|
|
Arthritis
|
An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain. C2883
|
C2883
|
NCI Thesaurus
|
|
|
Bacteremia
|
A laboratory test result that indicates the presence of bacteria in the blood. C102993
|
C102993
|
NCI Thesaurus
|
|
|
Bleeding
|
The flow of blood from a ruptured blood vessel. C26791
|
C26791
|
NCI Thesaurus
|
|
|
Blood Clots
|
An aggregation of blood factors, primarily platelets and fibrin with entrapment of cellular elements, frequently causing vascular obstruction at the point of its formation. C27083
|
C27083
|
NCI Thesaurus
|
|
|
Bronchiolitis
|
Inflammation of the bronchioles characterized by swelling of the bronchioles and mucus accumulation. It is usually caused by the respiratory syncytial virus and affects children. Signs and symptoms include coughing, wheezing, and shortness of breath. C39658
|
C39658
|
NCI Thesaurus
|
|
|
Cardiac Arrhythmia
|
Any variation from the normal rate or rhythm (which may include the origin of the impulse and/or its subsequent propagation) in the heart. C2881
|
C2881
|
NCI Thesaurus
|
|
|
Cardiac Failure
|
Inability of the heart to pump blood at an adequate rate to meet tissue metabolic requirements. Clinical symptoms of heart failure include: unusual dyspnea on light exertion, recurrent dyspnea occurring in the supine position, fluid retention or rales, jugular venous distension, pulmonary edema on physical exam, or pulmonary edema on chest x-ray presumed to be cardiac dysfunction. C50577
|
C50577
|
NCI Thesaurus
|
|
|
Cardiomyopathy
|
A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive. C34830
|
C34830
|
NCI Thesaurus
|
|
|
Coronary artery abnormalities
|
One of two arteries that arise from the aortic sinuses of the ascending aorta and supply blood to the myocardium.:A condition that differs from the usual physical or mental state. C12843:C9440
|
C12843:C9440
|
NCI Thesaurus
|
|
|
COVID-19-Associated Acute liver injury
|
Acute liver injury caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). C171566
|
C171566
|
NCI Thesaurus
|
|
|
Deep Vein Thrombosis
|
A blood clot in a deep vein, predominantly in the lower extremity, but may include the pelvis or upper extremity. C49343
|
C49343
|
NCI Thesaurus
|
|
|
Delirium
|
A usually reversible condition characterized by the acute and sudden development of confusion, illusions, movement changes, inattentiveness, agitation, and hallucinations. Causes include drug abuse, poisoning, infectious processes, and fluid and electrolyte imbalance. C2981
|
C2981
|
NCI Thesaurus
|
|
|
Deterioration of prior chronic pulmonary diseases
|
In an declined condition.: Earlier in time or order.: A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema. C71686: C25629: C3199
|
C71686: C25629: C3199
|
NCI Thesaurus
|
|
|
Diabetic ketoacidosis (DKA)
|
The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids. C50530
|
C50530
|
NCI Thesaurus
|
|
|
Diarrhea
|
Watery bowel movements. C2987
|
C2987
|
NCI Thesaurus
|
|
|
End Stage Renal Disease
|
Long-standing and persistent renal disease with glomerular filtration rate (GFR) less than 15 ml/min. C9439
|
C9439
|
NCI Thesaurus
|
|
|
Endocarditis
|
Inflammation of the endocardium. C34582
|
C34582
|
NCI Thesaurus
|
|
|
Fibromyalgia/amplified pain syndrome
|
A chronic disorder of unknown etiology characterized by pain, stiffness, and tenderness in the muscles of neck, shoulders, back, hips, arms, and legs. Other signs and symptoms include headaches, fatigue, sleep disturbances, and painful menstruation.:A condition in which the nerves register normal stimuli (lack of tissue injury) as pain, resulting in feelings of intense pain with even minor sensory input. C87497:C119048
|
C87497:C119048
|
NCI Thesaurus
|
|
|
Gastroesophageal reflux disease (GERD)
|
A chronic disorder characterized by reflux of the gastric and/or duodenal contents into the distal esophagus. It is usually caused by incompetence of the lower esophageal sphincter. Symptoms include heartburn and acid indigestion. It may cause injury to the esophageal mucosa. C26781
|
C26781
|
NCI Thesaurus
|
|
|
Gastrointestinal hemorrhage
|
Bleeding originating from any part of the gastrointestinal tract. C48592
|
C48592
|
NCI Thesaurus
|
|
|
Intestinal perforation
|
A rupture in the wall of the small or large intestine due to traumatic or pathologic processes. C39611
|
C39611
|
NCI Thesaurus
|
|
|
Kawasaki Disease
|
A vasculitis characterized by inflammation of the arteries, particularly the coronary arteries. The vasculitis may lead to aneurysm formation and possibly, heart attacks. It affects young children who usually present with persistent high fever, redness of the mucous membranes of the mouth, redness of the palms and soles, skin rashes, lymphadenitis, and joint pain and swelling. C34825
|
C34825
|
NCI Thesaurus
|
|
|
Liver dysfunction
|
A finding that indicates abnormal liver function. C50634
|
C50634
|
NCI Thesaurus
|
|
|
Lung fibrosis
|
One of a pair of viscera occupying the pulmonary cavities of the thorax, the organs of respiration in which aeration of the blood takes place. As a rule, the right lung is slightly larger than the left and is divided into three lobes (an upper, a middle, and a lower or basal), while the left has two lobes (an upper and a lower or basal). Each lung is irregularly conical in shape, presenting a blunt upper extremity (the apex), a concave base following the curve of the diaphragm, an outer convex surface (costal surface), an inner or mediastinal surface (mediastinal surface), a thin and sharp anterior border, and a thick and rounded posterior border.:The formation of fibrous tissue. C12468:C3044
|
C12468:C3044
|
NCI Thesaurus
|
|
|
Meningitis/encephalitis
|
A disorder characterized by acute inflammation of the meninges of the brain and/or spinal cord.:An article used to connect words, phrases, or clauses representing alternatives; used to connect alternative terms for the same thing; used in correlation; used to correct or rephrase what was previously said; otherwise.:An inflammatory process affecting the brain parenchyma.Causes include viral infections and less frequently bacterial infections, toxins, and immune-mediated processes. C26828:C37998:C26760
|
C26828:C37998:C26760
|
NCI Thesaurus
|
|
|
Multisystem Inflammatory Syndrome in Adults (MIS-A)
|
A rare syndrome found in adults with positive test results for SARS-CoV-2 by polymerase chain reaction or antibody assays indicating recent infection that is marked by cardiovascular, gastrointestinal, dermatologic, and neurologic symptoms without severe respiratory illness. The most common signs and symptoms that have been reported to date include fever, low blood pressure, abdominal pain, vomiting, diarrhea, neck pain, rash, chest pain, and tiredness not attributable to other infections. C178502
|
C178502
|
NCI Thesaurus
|
|
|
Myocarditis/Pericarditis
|
Inflammation of the muscle tissue of the heart.:An inflammatory process affecting the pericardium. C34831:C34915
|
C34831:C34915
|
NCI Thesaurus
|
|
|
Myositis
|
An inflammatory process affecting the skeletal muscles. Causes include infections, injuries, and autoimmune disorders. C27578
|
C27578
|
NCI Thesaurus
|
|
|
New onset diabetes
|
Having no previous example or precedent or parallel; of a kind not seen before.:The start, beginning, or early stages.:A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization. C25586:C25279:C2985
|
C25586:C25279:C2985
|
NCI Thesaurus
|
|
|
Other, Specify
|
A directive to specify when the listed responses are not sufficient. C157101
|
C157101
|
NCI Thesaurus
|
|
|
Pancreatitis
|
Inflammation of the pancreas. C3306
|
C3306
|
NCI Thesaurus
|
|
|
Pediatric Multisystem Inflammatory Syndrome (MIS-C)
|
A rare syndrome temporally associated with COVID-19 in children, marked by persistent fever, inflammation (neutrophilia, elevated C-reactive protein (CRP), and lymphopenia), poor function in one or more organs, and other specific clinical and laboratory features not attributable to other infections. The characteristics of this syndrome appear to be similar to toxic shock syndrome and Kawasaki disease. The following variable signs and symptoms have been most commonly reported to date: coagulopathy, cardiac dysfunction, diarrhea, abdominal distension, other GI symptoms (with some children having positive stool tests for SARS-CoV-2), and acute kidney injury. Respiratory symptoms are not always a prominent feature in these cases. C172127
|
C172127
|
NCI Thesaurus
|
|
|
Peritonitis
|
Inflammation of the peritoneum due to infection by bacteria or fungi. Causes include liver disease, perforation of the gastrointestinal tract or biliary tract, and peritoneal dialysis. Patients usually present with abdominal pain and tenderness, fever, chills, and nausea and vomiting. It is an emergency medical condition that requires prompt medical attention and treatment. C26849
|
C26849
|
NCI Thesaurus
|
|
|
Physical disability/muscular weakness
|
Having substance or material existence; concerned with material things; of or pertaining to the body as distinguished from the mind or spirit.:Any physical or mental impairment that interferes with an individual's ability to perform desired activities.:A reduction in the strength of one or more muscles. C25618:C21007:C50658
|
C25618:C21007:C50658
|
NCI Thesaurus
|
|
|
Pneumonia
|
An acute, acute and chronic, or chronic inflammation focally or diffusely affecting the lung parenchyma, due to infections (viruses, fungi, mycoplasma, or bacteria), treatment (e.g. radiation), or exposure (inhalation) to chemicals. Symptoms include cough, shortness of breath, fevers, chills, chest pain, headache, sweating, and weakness. C3333
|
C3333
|
NCI Thesaurus
|
|
|
Post viral fatigue syndrome
|
Happening at a time subsequent to a reference time; later in time or order.:Having to do with a virus.:Overall tiredness and lack of energy.:A group of signs, symptoms, and clinicopathological characteristics that may or may not have a genetic basis and collectively define an abnormal condition. C38008:C27985:C3036:C28193
|
C38008:C27985:C3036:C28193
|
NCI Thesaurus
|
|
|
pulmonary aspergillosis
|
Relating to the lungs as the intended site of administration, where the pharmaceutical product is administered, usually by inhalation, for local action in the lower respiratory tract or for systemic action after absorption via the lower respiratory tract.:An infection that is caused by Aspergillus. C13304:C2886
|
C13304:C2886
|
NCI Thesaurus
|
|
|
Pulmonary Embolism
|
The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung. C50713
|
C50713
|
NCI Thesaurus
|
|
|
Seizure
|
Sudden, involuntary skeletal muscular contractions of cerebral or brain stem origin. C2962
|
C2962
|
NCI Thesaurus
|
|
|
Shock
|
A life-threatening condition that requires immediate medical intervention. It is characterized by reduced blood flow that may result in damage of multiple organs. Types of shock include cardiogenic, hemorrhagic, septic, anaphylactic, and traumatic shock. C35016
|
C35016
|
NCI Thesaurus
|
|
|
Stroke: intracerebral hemorrhage
|
Bleeding within the cerebrum. C50485
|
C50485
|
NCI Thesaurus
|
|
|
Stroke: ischemic cerebrovascular accident
|
An acute episode of focal cerebral, spinal, or retinal dysfunction caused by infarction of brain tissue. C95802
|
C95802
|
NCI Thesaurus
|
|
|
Toxic shock syndrome
|
A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. It is characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria. C35498
|
C35498
|
NCI Thesaurus
|
|
|
Venus Thromboembolism (VTE)
|
Occlusion of the lumen of a vein by a thrombus that has migrated from a distal site via the blood stream. C99537
|
C99537
|
NCI Thesaurus
|