Name Steward Organization Suggested Domain Suggested Domain Description Cde Group Classification
Atherosclerosis small vessel disease cardiac source other cause (ASCO) system - other grade NINDS Disease characterization
Including Alzheimer's Disease (AD)/AD-Related Dementias (ADRD) diagnosis and multiple chronic conditions (MCCs)
NIH CDEs
  • NINDS
    • Disease
      • Stroke
        • Classification
          • Supplemental
        • Domain
          • Disease/Injury Related Events
            • Classification
    • Domain
      • Disease/Injury Related Events
        • Classification
    • Population
      • Adult

# Datatype
Value List

# Permissible value Value meaning name Value meaning definition
0 No disease is present No disease is present
1 Definitely a potential cause of the index stroke (examples): (a) Arterial dissection by A or B evidence (table 3), (b) Dolichoectasia with complicated aneurysm, (c) Polycythemia vera, thrombocythemia >800,000/mm3, (d) Lupus erythematosus, (e) Disseminated intravascular coagulation, (f) Criteria for antiphospholipid antibody syndrome, (g) Fabry's disease, (h) Concomitant meningitis, (i) Sickle cell disease, (j) Ruptured cerebral aneurysm with or without demonstration of spasm in the territory of the brain infarct, (k) Homozygote for hyperhomocystinuria Definitely a potential cause of the index stroke (examples): (a) Arterial dissection by A or B evidence (table 3), (b) Dolichoectasia with complicated aneurysm, (c) Polycythemia vera, thrombocythemia >800,000/mm3, (d) Lupus erythematosus, (e) Disseminated intravascular coagulation, (f) Criteria for antiphospholipid antibody syndrome, (g) Fabry's disease, (h) Concomitant meningitis, (i) Sickle cell disease, (j) Ruptured cerebral aneurysm with or without demonstration of spasm in the territory of the brain infarct, (k) Homozygote for hyperhomocystinuria
2 Causality uncertain: (a) Arterial dissection diagnosed by level C evidence, (b) Fibromuscular dysplasia Causality uncertain: (a) Arterial dissection diagnosed by level C evidence, (b) Fibromuscular dysplasia
3 Unlikely a direct cause of index stroke (but disease is present): (a) Kinking or dolichoectasia without complicated aneurysm or plicature, (b) Arteriovenous malformation or saccular aneurysm, (c) Thrombocytosis >450,000 and <800,000/mm3, (d) Antiphospholipid antibodies <100 GPL units, (e) Mild hyperhomocysteinemia heterozygote Unlikely a direct cause of index stroke (but disease is present): (a) Kinking or dolichoectasia without complicated aneurysm or plicature, (b) Arteriovenous malformation or saccular aneurysm, (c) Thrombocytosis >450,000 and <800,000/mm3, (d) Antiphospholipid antibodies <100 GPL units, (e) Mild hyperhomocysteinemia heterozygote
9 Cannot be graded because no tests were performed Cannot be graded because no tests were performed

# Definition
The grade of other cause, as part of the atherosclerosis small-vessel disease cardiac source other cause (ASCO) system. Patients are evaluated for the predefined phenotype of other cause (O)

# Designation
Atherosclerosis small vessel disease cardiac source other cause (ASCO) system - other grade

# Identifier Origin Version
ASCOSystemOtherGrade BRICS Variable Name N/A
C14233 NINDS 3
SQft3ARSSuX NLM CDEs 12-02-2025-download