| Name | Steward Organization | Suggested Domain | Suggested Domain Description | Cde Group | Classification |
|---|---|---|---|---|---|
| Infant NICU factors that affect newborn screening interpretation | NLM | Disease characterization |
Including Alzheimer's Disease (AD)/AD-Related Dementias (ADRD) diagnosis and multiple chronic conditions (MCCs) |
NIH CDEs |
|
| # | Datatype |
|---|---|
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|
Value List |
| # | Permissible value | Value meaning name | Value meaning code | Code system name |
|---|---|---|---|---|
|
|
Acute illness | Acute illness | LA25803-0 | LOINC |
|
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Any blood product transfusion (including ECLS/ECMO) | Any blood product transfusion (including ECLS/ECMO) | LA12417-4 | LOINC |
|
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Dopamine | Dopamine | LA16923-7 | LOINC |
|
|
Hypothyroxinemia of preterm birth | Hypothyroxinemia of preterm birth | LA25804-8 | LOINC |
|
|
Immature hypothalamic/pituitary axis | Immature hypothalamic/pituitary axis | LA25805-5 | LOINC |
|
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Immature liver enzymes | Immature liver enzymes | LA25806-3 | LOINC |
|
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Immature renal system | Immature renal system | LA25807-1 | LOINC |
|
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Immunosuppressive therapy of baby or mother | Immunosuppressive therapy of baby or mother | LA25808-9 | LOINC |
|
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Infant in NICU at time of specimen collection | Infant in NICU at time of specimen collection | LA12419-0 | LOINC |
|
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Infant in special care setting (other than ICU) at time of specimen collection | Infant in special care setting (other than ICU) at time of specimen collection | LA25801-4 | LOINC |
|
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Iodine deficiency | Iodine deficiency | LA25809-7 | LOINC |
|
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Liver disease | Liver disease | LA25810-5 | LOINC |
|
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Meconium ileus or other bowel obstruction | Meconium ileus or other bowel obstruction | LA16927-8 | LOINC |
|
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None | None | LA137-2 | LOINC |
|
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Other | Other | LA46-8 | LOINC |
|
|
Other conditions, such as biliary atresia, intestinal perforation, abdominal wall defects, septicemia, CMV, renal failure, T21, T18, T13 | Other conditions, such as biliary atresia, intestinal perforation, abdominal wall defects, septicemia, CMV, renal failure, T21, T18, T13 | LA25811-3 | LOINC |
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Parenteral steroid treatment | Parenteral steroid treatment | LA16925-2 | LOINC |
|
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Preterm/Low birth weight (LBW) | Preterm/Low birth weight (LBW) | LA25802-2 | LOINC |
|
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Significant hypoxia | Significant hypoxia | LA25812-1 | LOINC |
|
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Special lactose-free diet | Special lactose-free diet | LA25813-9 | LOINC |
|
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Special low protein diet | Special low protein diet | LA25814-7 | LOINC |
|
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Systemic antibiotics before newborn screening | Systemic antibiotics before newborn screening | LA12420-8 | LOINC |
|
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Thoracic surgery involving thymectomy | Thoracic surgery involving thymectomy | LA25815-4 | LOINC |
|
|
Topical iodine | Topical iodine | LA16924-5 | LOINC |
|
|
Total parenteral nutrition (TPN) or similar feeding | Total parenteral nutrition (TPN) or similar feeding | LA25816-2 | LOINC |
| # | Name | Origin | Origin | Concept type |
|---|---|---|---|---|
|
|
Find [Finding] | LOINC - Part - Property | LP6813-2 | property |
|
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Patient | LOINC - Part - Super System | LP6985-8 | property |
|
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newborn | LOINC - Part - Fragments for synonyms | LP91459-5 | property |
|
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Screening | LOINC - Part - Fragments for synonyms | LP34059-3 | property |
|
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P' | LOINC - Part - Fragments for synonyms | LP75922-2 | property |
|
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Pt [Point in time (spot)] | LOINC - Part - Time | LP6960-1 | property |
|
|
Nom | LOINC - Part - Scale | LP7750-5 | property |
|
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Infant NICU factors that affect newborn screening interpretation | LOINC - Part - Component | LP133643-9 | object |
| # | Definition | Tags |
|---|---|---|
|
|
Use this term to record various infant factors (also known as events), including treatments or conditions, that occur prior to collection of the newborn screening (NBS) specimen, and can affect the interpretation of NBS results. Select any answers that apply; you can select more than one answer. If you select "other," use the additional narrative LOINC code for "Other infant NICU factors that affect newborn screening interpretation" to give additional details. Select the answer "Infant in ICU at time of specimen collection" if the infant was in an intensive care unit, neonatal intensive care unit (NICU) or special care baby unit (SCBU). ECMO (extra corporeal membrane oxygenation, aka heart-lung bypass) can affect NBS results for hemoglobinopathies and GALT. Dopamine can affect NBS results for TSH. Steroid treatment can affect NBS results for TSH and 17-OHP. Iodine can affect NBS results for TSH and T4. Antibiotics can affect NBS results for C5. Some anti-seizure medications can affect NBS results for fatty acids. In screening for cystic fibrosis (CF), those babies presenting with meconium ileus or other bowel obstruction often have falsely low IRT's, so some states when they have that information, skip the IRT and go directly to DNA for their screen. SOURCES: Newborn Screening Guidelines for Preterm, Low Birth Weight, and Sick Newborns; Approved Guideline. CLSI document I/LA31-A. Wayne, PA: Clinical and Laboratory Standards Institute; (2009). LABORATORY MEDICINE PRACTICE GUIDELINES: FOLLOW-UP TESTING FOR METABOLIC DISEASES IDENTIFIED BY EXPANDED NEWBORN SCREENING USING TANDEM MASS SPECTROMETRY, The National Academy of Clinical Biochemistry, 2009 http://www.aacc.org/members/nacb/lmpg/onlineguide/publishedguidelines/newborn/pages/default.aspx. Utah Department of Health's "Newborn Screening For Sick or Preterm Newborns" Available at: http://health.utah.gov/newbornscreening/PDF/SupportProcScreeningSickPreterm.pdf. | TERM DEFINITION/DESCRIPTION(S) |
| # | Designation | Tags |
|---|---|---|
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Inf NICU factors affecting NBS imp | Shortname |
|
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Infant NICU factors that affect newborn screening interpretation | Long Common Name Question Text |
| # | Identifier | Origin | Version |
|---|---|---|---|
|
|
QyCe2Jx82Qz | NLM CDEs | 12-02-2025-download |
|
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57713-0 | LOINC | 2.56 |