Name Steward Organization Suggested Domain Suggested Domain Description Cde Group Classification
Biomarker muscle biochemistry assessment type NINDS Biomarkers, genetics, and genomics
Biomarkers, genetics, and genomics relevant to AD/ADRD
 NIH CDEs
  • ▼ NINDS
    • ▼ Disease
      • ▼ General (For all diseases)
        • ▼ Classification
          • Supplemental
        • ▼ Domain
          • ▼ Assessments and Examinations
            • Laboratory Tests and Biospecimens/Biomarkers
      • ▼ Mitochondrial Disease
        • ▼ Classification
          • Supplemental
        • ▼ Domain
          • ▼ Assessments and Examinations
            • Laboratory Tests and Biospecimens/Biomarkers
    • ▼ Domain
      • ▼ Assessments and Examinations
        • Laboratory Tests and Biospecimens/Biomarkers
    • ▼ Population
      • Adult
      • Pediatric

# Datatype

UUID: 52b16558-af2d-5c4a-a00e-70cde74d89b6

Value List

# Permissible value Value meaning name Value meaning definition

UUID: 1183ce7f-598d-5fdd-8478-bf8283ede77d

8-oxoguanine DNA glycolase-1 (OCG-1) 8-oxoguanine DNA glycolase-1 (OCG-1) 8-oxoguanine DNA glycolase-1 (OCG-1)

UUID: a07bdb4d-9890-5265-935f-566dceeacd03

Aconitase enzymology Aconitase enzymology Aconitase enzymology

UUID: 5c5fb404-7fba-52be-9141-155480666861

AIF AIF AIF

UUID: 31f14d38-60dd-59eb-b744-99da18474d7e

Bcl-2 Bcl-2 Bcl-2

UUID: 27f42b79-790b-5036-b680-b15019b47a77

Biogenesis regulator peroxisome proliferator-activated receptor-gamma coactivator- 1 alpha (PGC-1alpha) Biogenesis regulator peroxisome proliferator-activated receptor-gamma coactivator- 1 alpha (PGC-1alpha) Biogenesis regulator peroxisome proliferator-activated receptor-gamma coactivator- 1 alpha (PGC-1alpha)

UUID: 480ad4e6-006c-5073-8a21-28196521ebfa

Blue native gel electrophoresis Blue native gel electrophoresis Blue native gel electrophoresis

UUID: 9dd2ab58-f267-5a99-852c-0d7e9742f17e

clear native gel OXPHOS enzymology clear native gel OXPHOS enzymology clear native gel OXPHOS enzymology

UUID: 30a9f4c1-2aab-51c3-8f06-f81d1acf9e29

clear native gel OXPHOS immunoblot clear native gel OXPHOS immunoblot clear native gel OXPHOS immunoblot

UUID: b9c044fb-c13b-58b7-b9a8-f1d6eb2b219f

Coenzyme Q10 Coenzyme Q10 Coenzyme Q10

UUID: e06415aa-745d-5ddc-ad90-3ee2d1c1a987

Glutathione Glutathione Glutathione

UUID: 9e82ded5-e0d8-5104-abf4-b5c756522daa

High resolution respirometry High resolution respirometry High resolution respirometry

UUID: 120106d1-00d1-50e6-808a-9d58aec4dab0

Human mitochondrial transcription factor A (hmTFA or Tfam) Human mitochondrial transcription factor A (hmTFA or Tfam) Human mitochondrial transcription factor A (hmTFA or Tfam)

UUID: 51399477-2c3e-5f19-b887-dd8ac9a1b0f2

Manganese superoxide dismutase (MnSOD) Manganese superoxide dismutase (MnSOD) Manganese superoxide dismutase (MnSOD)

UUID: ca02db43-b719-5663-85fe-24d5948e0cca

Mitochondrial DNA absence factor (midas) Mitochondrial DNA absence factor (midas) Mitochondrial DNA absence factor (midas)

UUID: 4cf320ac-3a3d-535b-bffe-8c4b9cb3e7b4

mtDNA copy number mtDNA copy number mtDNA copy number

UUID: 367a5c43-00be-5fbe-aa66-f105da9728b5

mtDNA deletion/duplication mtDNA deletion/duplication mtDNA deletion/duplication

UUID: 5c6285c1-7256-5441-9c2a-a643b1beac21

OXPHOS enzymology OXPHOS enzymology OXPHOS enzymology

UUID: aec08a60-c9ac-5b31-815c-9c2a57e58fb9

OXPHOS subunit western blot OXPHOS subunit western blot OXPHOS subunit western blot

UUID: 4fd0a292-e5f7-588f-aed8-383f3241efd8

pyruvate dehydrogenase enzymology pyruvate dehydrogenase enzymology pyruvate dehydrogenase enzymology

UUID: fc2c267e-e7cf-5a5a-8932-32d498b86a37

pyruvate dehydrogenase subunit western blot pyruvate dehydrogenase subunit western blot pyruvate dehydrogenase subunit western blot

# Definition

UUID: f0364e45-223c-5cd5-80e5-fbde9c61b399

Type of biomarker(s) assessed from muscle biochemistry.

# Designation

UUID: 31e97458-be5d-5026-b72b-f7944183ede0

Biomarker muscle biochemistry assessment type

# Identifier Origin Version

UUID: aae1a459-3139-5aa8-a85f-7661bcf86a49

C19564 NINDS 1

UUID: 4a719204-c490-5cb5-98a0-977ec83a544e

BiomarkMuscBiochAssessTyp BRICS Variable Name N/A

UUID: b30d0196-9344-5ab9-8536-7be63d7af783

7kztlU49jr0 NLM CDEs 12-02-2025-download