Name Steward Organization Suggested Domain Suggested Domain Description Cde Group Classification
Adverse event severity grade scale NINDS Health outcomes
Patient and caregiver health outcomes
 NIH CDEs
  • ▼ NHLBI
    • ▼ Sickle Cell Disease
      • ▼ Domain
        • ▼ Safety Data
          • Adverse Events
      • ▼ Classification
        • Proposed
    • ▼ Venous Thromboembolism (VTE)
      • ▼ Adverse Events
        • ▼ Severity
          • Characteristics
  • ▼ NINDS
    • ▼ Disease
      • ▼ Epilepsy
        • ▼ Classification
          • Supplemental
        • ▼ Domain
          • ▼ Safety Data
            • Adverse Events
      • ▼ General (For all diseases)
        • ▼ Classification
          • Supplemental
        • ▼ Domain
          • ▼ Safety Data
            • Adverse Events
      • ▼ Parkinson's Disease
        • ▼ Classification
          • Supplemental
        • ▼ Domain
          • ▼ Treatment/Intervention Data
            • Surgeries and Other Procedures
      • ▼ Spinal Cord Injury
        • ▼ Classification
          • Supplemental
        • ▼ Domain
          • ▼ Assessments and Examinations
            • Hospital/Care Management
    • ▼ Domain
      • ▼ Assessments and Examinations
        • Hospital/Care Management
      • ▼ Safety Data
        • Adverse Events
      • ▼ Treatment/Intervention Data
        • Surgeries and Other Procedures
    • ▼ Population
      • Adult
      • Pediatric

# Datatype

UUID: 2b5e0a8a-c9f4-5f16-86a6-72932926ace6

Value List

# Permissible value Value meaning name Value meaning definition

UUID: 58a50ff9-cf80-5517-9f0f-d303b94b3333

Grade 1 Grade 1 Mild: asymptomatic or mild symtoms, clinical or diagnostic observations only, intervention not indicated.

UUID: 6accd6c6-61af-568c-aa69-d2d66366f218

Grade 2 Grade 2 Moderate: minimal, local or noninvasive intervention indicated, limiting age-appropriate Activities of Daily Living.

UUID: 868a08bb-790c-565c-966a-38b3e2eaf09b

Grade 3 Grade 3 Severe or medically significant but not immediately life-threatening: hospitalization or prolongation of hospitalization indicated, disabling, limiting self care Activities of Daily Living

UUID: 0310102c-6d7f-5402-862d-855335409b69

Grade 4 Grade 4 Life-threatening consequences: urgent intervention indicated

UUID: a2f85f71-9444-57db-a722-8f7efe54ac70

Grade 5 Grade 5 Death related to adverse event

# Definition

UUID: 339db72c-dcf2-5a83-aa02-b164b659d73b

The grading scale of the severity or intensity of the adverse event

UUID: 3befe094-6201-5a78-8d12-d0f6164b8a8d

The severity of the adverse event.

# Designation Tags

UUID: aa8e8a0e-fbc2-5230-8639-b2cdefdc6a31

Adverse event severity grade scale

UUID: 05f63710-b479-572c-92d8-04ba808d70c0

Adverse Event Severity

UUID: 6d531898-01cb-50f7-8ac8-8891c4e6b1b2

AE Grade Suggested Question Text

# Identifier Origin Version

UUID: 68677b2e-4370-507d-bec3-b3395b35d981

Su71nJ0K1WH NLM CDEs 12-02-2025-download

UUID: 94863912-af5c-5896-ad7e-05da7bf2fb00

1:83:6:437 ISTH N/A

UUID: 753fa905-ce2d-5118-a990-bfe9c4af884b

C02305 NINDS 4

UUID: 41bf05c8-6286-50f7-b61e-a99905ae688b

2201188 NINDS caDSR N/A

UUID: ca76157c-366a-5293-8e96-f7bb251ae17c

AdvrsEvntSeverScale BRICS Variable Name N/A